(1.) The Pesticides Board

Consists of nominees from the Agricultural Chemicals and Animal Remedies Manufacturers Association Inc., the Departments of Environment, Agriculture, Science and Health, the New Zealand Vegetable and Product Growers' Federation Inc., the New Zealand Fruitgrowers' Federation Ltd, Federated Farmers of New Zealand Inc., and the Wine Institute of New Zealand.

The Pesticides Board demands the LD50 "test" for any pesticide being imported (registered).

The Requirements are laid down in "Procedures for Registration and Experimental Use Permits Under the Pesticides Act 1979" dated 1 October 1982: Brief extracts from which are shown:

Acute oral toxicity		"Data for both sexes of animals of at least three species, one of which is not a rodent, should be supplied. LD50 figures required"
Inhalation toxicity		"Required if the chemical has a high vapour pressure or if the formulation is used as a gas, fog, smoke, fumigant or contains respirable dust. To contain results from two species."
Skin irritation		"At least one species should be utilised being usually either the rat or the rabbit."
Eye irritation		"The rabbit is usually the species of choice."
Allergic sensitization		"The guinea pig is usually the most appropriate species."
Sub-acute toxicity studies		"Dosing of at least two species including the rat and one rodent is desirable usually for at least three months or up to one tenth of their life-span."
Teratology/reproduction studies		"Minimum studies acceptable are for two species (usually rat, mouse or rabbit) dosed over a period. To be continued for three generations."
Mutagenicity studies		"No single procedure - but a battery of tests recommended"

Pages 18 and 19 of the above publication give demand for LD50 on birds, fish, bees, insects.

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